There are many production methods for this product, but there are mainly three methods using aniline, o-nitrochlorobenzene and diphenylthiourea as raw materials. 

Using aniline as the raw material, aniline, carbon disulfide and sulfur are usually reacted directly in the autoclave, and aliphatic amine, dimethylformamide, trithiazolidine and polyformaldehyde can also be used to replace carbon disulfide, so that under the pressure of aniline and sulfur, reaction. The method using aniline as the raw material has a high reaction pressure, generally above 4MPa, and as high as 15MPa, so it is also called the high-pressure method by Chemicalbook.

Using o-nitrochlorobenzene as raw material, o-nitrochlorobenzene can be reduced to o-aminothiophenol by reaction with reducing agent sodium hydrosulfide, sodium polysulfide or hydrogen sulfide. Accelerator M is prepared by further reacting with carbon disulfide. Some of these methods have a longer reaction time (about 20h for sodium hydrosulfide), but they can all be carried out at normal pressure or lower pressure, also known as normal pressure method.

Using diphenylthiourea as raw material, the reaction pressure of this method is between the above two methods, below 4MPa, which is generally called the medium pressure method.